Varaico: Literature-Extracted Genetic Variants

Gene:BCAR3
Variant:p.C561G

BCAR3

202 papers

RefSeq Summary

Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resista...

Pfam Domains

SH2aa 154–234UCSCSH2 domain
RasGEFaa 551–730UCSCRasGEF domain

Gene Aliases

HGNC Name

BCAR3 adaptor protein, NSP family member

HGNC Alias Symbols

NSP2; SH2D3B; AND-34; MIG7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003567.4
p.C561G
c.1681T>G
Surrounding Variants
1 paper
NM_003567.4
p.C561S
c.1681T>A
1 paper
NM_003567.4
p.C561S
c.1682G>C
1 paper
NM_003567.4
p.D548V
c.1643A>T
1 paper
NM_003567.4
p.R539S
c.1615C>A
1 paper
NM_003567.4
p.M536L
c.1606A>T
1 paper
NM_003567.4
p.M536L
c.1606A>C
1 paper
NM_003567.4
p.F515L
c.1545C>G
1 paper
NM_003567.4
p.F515L
c.1545C>A
1 paper
NM_003567.4
p.F515L
c.1543T>C
4 papers
NM_003567.4
p.Q498R
c.1493A>G
7 papers
NM_003567.4
p.Q493R
c.1478A>G
2 papers
NM_003567.4
p.A490V
c.1469C>T
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