Varaico: Literature-Extracted Genetic Variants

Gene:BCAR3
Variant:p.H69del1

BCAR3

202 papers

RefSeq Summary

Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resista...

Pfam Domains

SH2aa 154–234UCSCSH2 domain
RasGEFaa 551–730UCSCRasGEF domain

Gene Aliases

HGNC Name

BCAR3 adaptor protein, NSP family member

HGNC Alias Symbols

NSP2; SH2D3B; AND-34; MIG7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
5 papers
NM_003567.4
p.H69del1
c.205_206delGTG
Surrounding Variants
1 paper
NM_003567.4
p.M70I
c.210G>T
1 paper
NM_003567.4
p.P74P
c.222C>T
8 papers
NM_003567.4
p.Q81*
c.241C>T
1 paper
NM_003567.4
p.G57fs
c.169_170fs
1 paper
NM_003567.4
p.R53Q
c.158G>A
1 paper
NM_003567.4
p.R53W
c.157C>T
1 paper
NM_003567.4
p.Q87Q
c.261G>A
1 paper
NM_003567.4
p.D88H
c.262G>C
3 papers
NM_003567.4
p.G89R
c.265G>C
1 paper
NM_003567.4
p.I90T
c.269T>C
1 paper
NM_003567.4
p.G49D
c.146G>A
1 paper
NM_003567.4
p.E92K
c.274G>A
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