Varaico: Literature-Extracted Genetic Variants

BCR

1,586 papers

RefSeq Summary

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this ...

Pfam Domains

Bcr-Abl_Oligoaa 3–75UCSCBcr-Abl oncoprotein oligomerisation domain

RhoGEFaa 502–689UCSCRhoGEF domain

PH_19aa 697–823UCSCPH domain

C2aa 911–1018UCSCC2 domain

RhoGAPaa 1068–1216UCSCRhoGAP domain

Gene Aliases

HGNC Name

BCR activator of RhoGEF and GTPase

HGNC Previous Symbols

D22S11; BCR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004327.4

p.D106del1

c.316_318delGAC

Surrounding Variants

1 paper

NM_004327.4

p.P107insFs

c.319_320ins7

1 paper

NM_004327.4

p.A105_D106ins7

c.315_316ins21

2 papers

NM_004327.4

p.A105A

c.315C>T

1 paper

NM_004327.4

p.P107delFs

c.319_320delCC

1 paper

NM_004327.4

p.A105_D106delFs

c.313_317del5

1 paper

NM_004327.4

p.A102T

c.304G>A

1 paper

NM_004327.4

p.A102insFs

c.304_305ins10

1 paper

NM_004327.4

p.P108P

c.324G>T

1 paper

NM_004327.4

p.P101P

c.303C>T

1 paper

NM_004327.4

p.P101H

c.302C>A

1 paper

NM_004327.4

p.P109P

c.327C>A

1 paper

NM_004327.4

p.A110_E112del3

c.328_335del9