Varaico: Literature-Extracted Genetic Variants

BCR

1,586 papers

RefSeq Summary

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this ...

Pfam Domains

Bcr-Abl_Oligoaa 3–75UCSCBcr-Abl oncoprotein oligomerisation domain

RhoGEFaa 502–689UCSCRhoGEF domain

PH_19aa 697–823UCSCPH domain

C2aa 911–1018UCSCC2 domain

RhoGAPaa 1068–1216UCSCRhoGAP domain

Gene Aliases

HGNC Name

BCR activator of RhoGEF and GTPase

HGNC Previous Symbols

D22S11; BCR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004327.4

p.P384_T385insFs

c.1152_1153insA

Surrounding Variants

1 paper

NM_004327.4

p.T385insFs

c.1154_1155ins5

1 paper

NM_004327.4

p.T385_P386insFs

c.1155_1156ins5

5 papers

NM_004327.4

p.T385insFs

c.1154_1155ins5

1 paper

NM_004327.4

p.T385Fs

c.1154delinsGTTGTCFs

1 paper

NM_004327.4

p.T385Fs

c.1154delinsTATGTCFs

1 paper

NM_004327.4

p.T385insFs

c.1153_1154ins5

1 paper

NM_004327.4

p.T385Fs

c.1154delinsTGTGTCFs

1 paper

NM_004327.4

p.T385Fs

c.1154delinsTTTATCFs

1 paper

NM_004327.4

p.T385Fs

c.1154delinsTTTGTCFs

1 paper

NM_004327.4

p.T385P

c.1153A>C

1 paper

NM_004327.4

p.T385S

c.1153A>T

1 paper

NM_004327.4

p.T385Fs

c.1153_1154delinsTCTTGTCFs