Varaico: Literature-Extracted Genetic Variants

BIRC2

175 papers

RefSeq Summary

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering wi...

Pfam Domains

BIRaa 49–114UCSCInhibitor of Apoptosis domain

BIRaa 187–251UCSCInhibitor of Apoptosis domain

BIRaa 272–337UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 388–440UCSCBIRC2/3-like, UBA domain

CARDaa 458–542UCSCCaspase recruitment domain

zf-C3HC4_3aa 567–612UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

baculoviral IAP repeat containing 2

HGNC Previous Symbol

API1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001166.5

p.E23A

c.68A>C

Surrounding Variants

1 paper

NM_001166.5

p.M22I

c.66G>A

1 paper

NM_001166.5

p.M22L

c.64A>C

1 paper

NM_001166.5

p.M22L

c.64A>T

1 paper

NM_001166.5

p.T26T

c.78G>A

1 paper

NM_001166.5

p.K19fs

c.55_56fs

1 paper

NM_001166.5

p.K19delFs

c.55delA

1 paper

NM_001166.5

p.S29P

c.85T>C

1 paper

NM_001166.5

p.W31*

c.93G>A

2 papers

NM_001166.5

p.G12D

c.35G>A

1 paper

NM_001166.5

p.G12S

c.34G>A

1 paper

NM_001166.5

p.K38delFs

c.112_113delAA

1 paper

NM_001166.5

p.L9R

c.26T>G