Varaico: Literature-Extracted Genetic Variants

BIRC2

175 papers

RefSeq Summary

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering wi...

Pfam Domains

BIRaa 49–114UCSCInhibitor of Apoptosis domain

BIRaa 187–251UCSCInhibitor of Apoptosis domain

BIRaa 272–337UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 388–440UCSCBIRC2/3-like, UBA domain

CARDaa 458–542UCSCCaspase recruitment domain

zf-C3HC4_3aa 567–612UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

baculoviral IAP repeat containing 2

HGNC Previous Symbol

API1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001166.5

p.S152A

c.454T>G

Surrounding Variants

1 paper

NM_001166.5

p.S154A

c.460T>G

1 paper

NM_001166.5

p.L156F

c.466C>T

1 paper

NM_001166.5

p.S146I

c.437G>T

1 paper

NM_001166.5

p.A136E

c.407C>A

1 paper

NM_001166.5

p.S170P

c.508T>C

1 paper

NM_001166.5

p.T128S

c.382A>T

1 paper

NM_001166.5

p.A119P

c.355G>C

1 paper

NM_001166.5

p.T190A

c.568A>G

1 paper

NM_001166.5

p.F112_I113del2

c.334_338del6

1 paper

NM_001166.5

p.L196V

c.586T>G

1 paper

NM_001166.5

p.T197fs

c.589_590fs

1 paper

NM_001166.5

p.T197delFs

c.591delT