Varaico: Literature-Extracted Genetic Variants

BIRC2

175 papers

RefSeq Summary

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering wi...

Pfam Domains

BIRaa 49–114UCSCInhibitor of Apoptosis domain

BIRaa 187–251UCSCInhibitor of Apoptosis domain

BIRaa 272–337UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 388–440UCSCBIRC2/3-like, UBA domain

CARDaa 458–542UCSCCaspase recruitment domain

zf-C3HC4_3aa 567–612UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

baculoviral IAP repeat containing 2

HGNC Previous Symbol

API1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001166.5

p.T197delFs

c.591delT

Surrounding Variants

1 paper

NM_001166.5

p.T197fs

c.589_590fs

1 paper

NM_001166.5

p.L196V

c.586T>G

1 paper

NM_001166.5

p.L199fs

c.595_596fs

1 paper

NM_001166.5

p.S202P

c.604T>C

2 papers

NM_001166.5

p.S202*

c.605C>A

1 paper

NM_001166.5

p.S202*

c.605C>G

1 paper

NM_001166.5

p.T190A

c.568A>G

1 paper

NM_001166.5

p.A207P

c.619G>C

1 paper

NM_001166.5

p.S170P

c.508T>C

1 paper

NM_001166.5

p.K226N

c.678G>T

1 paper

NM_001166.5

p.L227H

c.680T>A

1 paper

NM_001166.5

p.D234A

c.701A>C