Varaico: Literature-Extracted Genetic Variants

BIRC2

175 papers

RefSeq Summary

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering wi...

Pfam Domains

BIRaa 49–114UCSCInhibitor of Apoptosis domain

BIRaa 187–251UCSCInhibitor of Apoptosis domain

BIRaa 272–337UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 388–440UCSCBIRC2/3-like, UBA domain

CARDaa 458–542UCSCCaspase recruitment domain

zf-C3HC4_3aa 567–612UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

baculoviral IAP repeat containing 2

HGNC Previous Symbol

API1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001166.5

p.L313F

c.939G>C

Surrounding Variants

1 paper

NM_001166.5

p.L313F

c.939G>T

1 paper

NM_001166.5

p.L313S

c.938T>C

1 paper

NM_001166.5

p.W316R

c.946T>A

1 paper

NM_001166.5

p.W316R

c.946T>C

1 paper

NM_001166.5

p.S318P

c.952T>C

1 paper

NM_001166.5

p.C309S

c.925T>A

1 paper

NM_001166.5

p.G319E

c.956G>A

1 paper

NM_001166.5

p.D320N

c.958G>A

2 papers

NM_001166.5

p.D320A

c.959A>C

1 paper

NM_001166.5

p.C306W

c.918C>G

1 paper

NM_001166.5

p.D303A

c.908A>C

1 paper

NM_001166.5

p.E325A

c.974A>C