Varaico: Literature-Extracted Genetic Variants

BIRC2

175 papers

RefSeq Summary

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering wi...

Pfam Domains

BIRaa 49–114UCSCInhibitor of Apoptosis domain

BIRaa 187–251UCSCInhibitor of Apoptosis domain

BIRaa 272–337UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 388–440UCSCBIRC2/3-like, UBA domain

CARDaa 458–542UCSCCaspase recruitment domain

zf-C3HC4_3aa 567–612UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

baculoviral IAP repeat containing 2

HGNC Previous Symbol

API1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001166.5

p.V573insFs

c.1717_1718ins5

Surrounding Variants

1 paper

NM_001166.5

p.V573fs

c.1717_1718fs

3 papers

NM_001166.5

p.V573A

c.1718T>C

2 papers

NM_001166.5

p.D576A

c.1727A>C

1 paper

NM_001166.5

p.E568*

c.1702G>T

1 paper

NM_001166.5

p.Q566H

c.1698A>C

1 paper

NM_001166.5

p.Q566H

c.1698A>T

1 paper

NM_001166.5

p.G587_V591del0

c.1760_1771del12

1 paper

NM_001166.5

p.R614G

c.1840C>G

1 paper

NM_001166.5

p.D552N

c.1654G>A

1 paper

NM_001166.5

p.K546_Y547insFs

c.1638_1639insA

1 paper

NM_001166.5

p.D542N

c.1624G>A

1 paper

NM_001166.5

p.V541Splc

c.1621+4A>G