Varaico: Literature-Extracted Genetic Variants

BIRC3

322 papers

RefSeq Summary

This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation...

Pfam Domains

BIRaa 32–97UCSCInhibitor of Apoptosis domain

BIRaa 172–236UCSCInhibitor of Apoptosis domain

BIRaa 258–323UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 374–426UCSCBIRC2/3-like, UBA domain

CARDaa 444–528UCSCCaspase recruitment domain

zf-C3HC4_3aa 553–598UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

baculoviral IAP repeat containing 3

HGNC Previous Symbol

API2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001165.5

p.M1_V4del0

c.1_12del12

Surrounding Variants

1 paper

NM_001165.5

p.M1L

c.1A>C

1 paper

NM_001165.5

p.M1L

c.1A>T

1 paper

NM_001165.5

p.M1_N12del12

c.1_35del36

1 paper

NM_001165.5

p.M1K

c.2T>A

1 paper

NM_001165.5

p.M1_N2insFs

c.3_4insA

1 paper

NM_001165.5

p.N2S

c.5A>G

1 paper

NM_001165.5

p.N6I

c.17A>T

1 paper

NM_001165.5

p.S7I

c.20G>T

1 paper

NM_001165.5

p.I8R

c.23T>G

1 paper

NM_001165.5

p.S11P

c.31T>C

1 paper

NM_001165.5

p.N12H

c.34A>C

1 paper

NM_001165.5

p.M14V

c.40A>G