Varaico: Literature-Extracted Genetic Variants

BIRC3

322 papers

RefSeq Summary

This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation...

Pfam Domains

BIRaa 32–97UCSCInhibitor of Apoptosis domain

BIRaa 172–236UCSCInhibitor of Apoptosis domain

BIRaa 258–323UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 374–426UCSCBIRC2/3-like, UBA domain

CARDaa 444–528UCSCCaspase recruitment domain

zf-C3HC4_3aa 553–598UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

baculoviral IAP repeat containing 3

HGNC Previous Symbol

API2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001165.5

p.N264T

c.791A>C

Surrounding Variants

1 paper

NM_001165.5

p.T261K

c.782C>A

5 papers

NM_001165.5

p.K260R

c.779A>G

1 paper

NM_001165.5

p.V269I

c.805G>A

1 paper

NM_001165.5

p.V271F

c.811G>T

1 paper

NM_001165.5

p.V271G

c.812T>G

2 papers

NM_001165.5

p.A257S

c.769G>T

1 paper

NM_001165.5

p.A256S

c.766G>T

1 paper

NM_001165.5

p.H255N

c.763C>A

1 paper

NM_001165.5

p.A277V

c.830C>T

1 paper

NM_001165.5

p.S278R

c.832A>C

1 paper

NM_001165.5

p.S278R

c.834T>A

1 paper

NM_001165.5

p.S278R

c.834T>G