Varaico: Literature-Extracted Genetic Variants

BIRC3

322 papers

RefSeq Summary

This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation...

Pfam Domains

BIRaa 32–97UCSCInhibitor of Apoptosis domain

BIRaa 172–236UCSCInhibitor of Apoptosis domain

BIRaa 258–323UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 374–426UCSCBIRC2/3-like, UBA domain

CARDaa 444–528UCSCCaspase recruitment domain

zf-C3HC4_3aa 553–598UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

baculoviral IAP repeat containing 3

HGNC Previous Symbol

API2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001165.5

p.V386delFs

c.1158delG

Surrounding Variants

5 papers

NM_001165.5

p.V386M

c.1156G>A

1 paper

NM_001165.5

p.V386fs

c.1156_1157fs

1 paper

NM_001165.5

p.A385D

c.1154C>A

2 papers

NM_001165.5

p.A385T

c.1153G>A

1 paper

NM_001165.5

p.M388V

c.1162A>G

1 paper

NM_001165.5

p.S391fs

c.1171_1172fs

1 paper

NM_001165.5

p.S391N

c.1172G>A

1 paper

NM_001165.5

p.P380fs

c.1138_1139fs

1 paper

NM_001165.5

p.N378K

c.1134T>A

1 paper

NM_001165.5

p.N378K

c.1134T>G

1 paper

NM_001165.5

p.V395fs

c.1183_1184fs

1 paper

NM_001165.5

p.V395A

c.1184T>C