Varaico: Literature-Extracted Genetic Variants

BIRC3

322 papers

RefSeq Summary

This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation...

Pfam Domains

BIRaa 32–97UCSCInhibitor of Apoptosis domain

BIRaa 172–236UCSCInhibitor of Apoptosis domain

BIRaa 258–323UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 374–426UCSCBIRC2/3-like, UBA domain

CARDaa 444–528UCSCCaspase recruitment domain

zf-C3HC4_3aa 553–598UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

baculoviral IAP repeat containing 3

HGNC Previous Symbol

API2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_001165.5

p.E429fs

c.1285_1286fs

Surrounding Variants

2 papers

NM_001165.5

p.E429insFs

c.1287dupA

2 papers

NM_001165.5

p.E429fs

c.1285_1286fs

1 paper

NM_001165.5

p.R428_E429insFs

c.1284_1285insA

1 paper

NM_001165.5

p.E429_E430delFs

c.1285_1289del5

1 paper

NM_001165.5

p.E430insFs

c.1288_1289insG

1 paper

NM_001165.5

p.E429_E430del2

c.1285_1289del6

3 papers

NM_001165.5

p.R428insFs

c.1283dupG

1 paper

NM_001165.5

p.R428fs

c.1282_1283fs

2 papers

NM_001165.5

p.E429delFs

c.1285delG

1 paper

NM_001165.5

p.R428fs

c.1282_1283fs

1 paper

NM_001165.5

p.E430fs

c.1288_1289fs

2 papers

NM_001165.5

p.E430fs

c.1288_1289fs