Varaico: Literature-Extracted Genetic Variants

BRAF

18,221 papers

RefSeq Summary

This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, ...

Pfam Domains

RBDaa 156–227UCSCRaf-like Ras-binding domain

C1_1aa 235–282UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PK_Tyr_Ser-Thraa 497–754UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

B-Raf proto-oncogene, serine/threonine kinase

HGNC Alias Symbols

BRAF1; BRAF-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004333.6

p.V482G

c.1445T>G

Surrounding Variants

1 paper

NM_004333.6

p.V482V

c.1446G>T

1 paper

NM_004333.6

p.V482V

c.1446G>A

1 paper

NM_004333.6

p.V482M

c.1444G>A

50 papers

NM_004333.6

p.K483E

c.1447A>G

9 papers

NM_004333.6

p.K483Q

c.1447A>C

2 papers

NM_004333.6

p.A481E

c.1442C>A

1 paper

NM_004333.6

p.A481delins

c.1441_1442delinsTT

2 papers

NM_004333.6

p.K483R

c.1448A>G

2 papers

NM_004333.6

p.K483T

c.1448A>C

6 papers

NM_004333.6

p.K483N

c.1449A>T

6 papers

NM_004333.6

p.K483N

c.1449A>C

1 paper

NM_004333.6

p.M484fs

c.1450_1451fs