Varaico: Literature-Extracted Genetic Variants

BRAF

18,221 papers

RefSeq Summary

This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, ...

Pfam Domains

RBDaa 156–227UCSCRaf-like Ras-binding domain

C1_1aa 235–282UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PK_Tyr_Ser-Thraa 497–754UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

B-Raf proto-oncogene, serine/threonine kinase

HGNC Alias Symbols

BRAF1; BRAF-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004333.6

p.G469G

c.1407A>C

Surrounding Variants

2 papers

NM_004333.6

p.G469G

c.1407A>T

1 paper

NM_004333.6

p.G469delins

c.1405_1407delinsAGT

312 papers

NM_004333.6

p.G469V

c.1406G>T

696 papers

NM_004333.6

p.G469A

c.1406G>C

NM_001374258.1

p.G509A

c.1526G>C

259 papers

NM_004333.6

p.G469E

c.1406G>A

3 papers

NM_004333.6

p.G469delins

c.1405_1406delinsTT

5 papers

NM_004333.6

p.G469delins

c.1405_1406delinsTC

1 paper

NM_004333.6

p.F468_G469delins

c.1404_1406delinsAAA

3 papers

NM_004333.6

p.T470A

c.1408A>G

7 papers

NM_004333.6

p.T470P

c.1408A>C

4 papers

NM_004333.6

p.G469del1

c.1405_1406delTCC

1 paper

NM_004333.6

p.S467_G469del3

c.1399_1406del9