Varaico: Literature-Extracted Genetic Variants

BRAF

18,221 papers

RefSeq Summary

This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, ...

Pfam Domains

RBDaa 156–227UCSCRaf-like Ras-binding domain

C1_1aa 235–282UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PK_Tyr_Ser-Thraa 497–754UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

B-Raf proto-oncogene, serine/threonine kinase

HGNC Alias Symbols

BRAF1; BRAF-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004333.6

p.A38G

c.113C>G

Surrounding Variants

2 papers

NM_004333.6

p.A38V

c.113C>T

1 paper

NM_004333.6

p.A38delins

c.112_113delinsTT

1 paper

NM_004333.6

p.A38A

c.114T>G

1 paper

NM_004333.6

p.A38P

c.112G>C

2 papers

NM_004333.6

p.S36_S37del2

c.106_110del6

6 papers

NM_004333.6

p.A39S

c.115G>T

1 paper

NM_004333.6

p.A39_D40insGGC

c.115_119ins9

5 papers

NM_004333.6

p.A39P

c.115G>C

6 papers

NM_004333.6

p.A39T

c.115G>A

1 paper

NM_004333.6

p.S37delFs

c.110delG

4 papers

NM_004333.6

p.A39V

c.116C>T

4 papers

NM_004333.6

p.S37L

c.110C>T