Varaico: Literature-Extracted Genetic Variants

BRAF

18,221 papers

RefSeq Summary

This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, ...

Pfam Domains

RBDaa 156–227UCSCRaf-like Ras-binding domain

C1_1aa 235–282UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PK_Tyr_Ser-Thraa 497–754UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

B-Raf proto-oncogene, serine/threonine kinase

HGNC Alias Symbols

BRAF1; BRAF-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004333.6

p.G32G

c.96C>G

Surrounding Variants

1 paper

NM_004333.6

p.G32insFs

c.95dupG

1 paper

NM_004333.6

p.G32G

c.96C>A

2 papers

NM_004333.6

p.A33S

c.97G>T

1 paper

NM_004333.6

p.A33_A34ins6

c.97_101ins18

1 paper

NM_004333.6

p.A33P

c.97G>C

1 paper

NM_004333.6

p.G32A

c.95G>C

2 papers

NM_004333.6

p.A33T

c.97G>A

2 papers

NM_004333.6

p.G32D

c.95G>A

1 paper

NM_004333.6

p.A27_G32delFs

c.81_96del16

1 paper

NM_004333.6

p.P25_G32delFs

c.75_96del22

2 papers

NM_004333.6

p.G32C

c.94G>T

4 papers

NM_004333.6

p.G32R

c.94G>C