Varaico: Literature-Extracted Genetic Variants

BRAF

18,221 papers

RefSeq Summary

This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, ...

Pfam Domains

RBDaa 156–227UCSCRaf-like Ras-binding domain

C1_1aa 235–282UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PK_Tyr_Ser-Thraa 497–754UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

B-Raf proto-oncogene, serine/threonine kinase

HGNC Alias Symbols

BRAF1; BRAF-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004333.6

p.A27insFs

c.79_80dupGC

Surrounding Variants

1 paper

NM_004333.6

p.A27A

c.81C>T

1 paper

NM_004333.6

p.E26_A27ins0

c.78_80dupGGC

1 paper

NM_004333.6

p.E26_A27insFs

c.77_80dup4

1 paper

NM_004333.6

p.A27fs

c.79_80fs

1 paper

NM_004333.6

p.E26_A27delFs

c.77_80del4

1 paper

NM_004333.6

p.E24_A27del0

c.72_80del9

1 paper

NM_004333.6

p.G28C

c.82G>T

1 paper

NM_004333.6

p.G28insFs

c.82_83insCG

1 paper

NM_004333.6

p.P25_A27insFs

c.74_80dup7

1 paper

NM_004333.6

p.G28S

c.82G>A

2 papers

NM_004333.6

p.A27V

c.80C>T

1 paper

NM_004333.6

p.A27G

c.80C>G