Varaico: Literature-Extracted Genetic Variants

BRAF

18,221 papers

RefSeq Summary

This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, ...

Pfam Domains

RBDaa 156–227UCSCRaf-like Ras-binding domain

C1_1aa 235–282UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PK_Tyr_Ser-Thraa 497–754UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

B-Raf proto-oncogene, serine/threonine kinase

HGNC Alias Symbols

BRAF1; BRAF-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004333.6

p.M23delFs

c.69delC

Surrounding Variants

1 paper

NM_004333.6

p.E24V

c.71A>T

2 papers

NM_004333.6

p.E24A

c.71A>C

1 paper

NM_004333.6

p.M23_E24insFs

c.69_70insG

1 paper

NM_004333.6

p.E24D

c.72G>T

1 paper

NM_004333.6

p.E24*

c.70G>T

1 paper

NM_004333.6

p.E24D

c.72G>C

2 papers

NM_004333.6

p.E24K

c.70G>A

1 paper

NM_004333.6

p.M23del1

c.67_68delCAT

2 papers

NM_004333.6

p.F19_M23del5

c.55_68del15

1 paper

NM_004333.6

p.M23_E24delFs

c.68_71del4

1 paper

NM_004333.6

p.M23I

c.69G>C

1 paper

NM_004333.6

p.M23I

c.69G>A