Varaico: Literature-Extracted Genetic Variants

BRAF

18,221 papers

RefSeq Summary

This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, ...

Pfam Domains

RBDaa 156–227UCSCRaf-like Ras-binding domain

C1_1aa 235–282UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PK_Tyr_Ser-Thraa 497–754UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

B-Raf proto-oncogene, serine/threonine kinase

HGNC Alias Symbols

BRAF1; BRAF-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_004333.6

p.E13delins

c.38_39delinsTT

Surrounding Variants

2 papers

NM_004333.6

p.E13delins

c.38_39delinsAT

1 paper

NM_004333.6

p.E13D

c.39G>C

1 paper

NM_004333.6

p.E13delins

c.38_39delinsAA

1 paper

NM_004333.6

p.E13_P14ins1

c.39_40insGGC

1 paper

NM_004333.6

p.A12_E13ins0

c.36_38dupGGA

1 paper

NM_004333.6

p.P14T

c.40C>A

1 paper

NM_004333.6

p.E13delins

c.38_39delinsAG

2 papers

NM_004333.6

p.E13G

c.38A>G

1 paper

NM_004333.6

p.A12insFs

c.36dupG

2 papers

NM_004333.6

p.A12_E13ins1

c.36_37insGGT

2 papers

NM_004333.6

p.A12_E13delFs

c.36_37delCC

1 paper

NM_004333.6

p.G10_A12delFs

c.30_34del5