Varaico: Literature-Extracted Genetic Variants

BRAF

18,221 papers

RefSeq Summary

This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, ...

Pfam Domains

RBDaa 156–227UCSCRaf-like Ras-binding domain

C1_1aa 235–282UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PK_Tyr_Ser-Thraa 497–754UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

B-Raf proto-oncogene, serine/threonine kinase

HGNC Alias Symbols

BRAF1; BRAF-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004333.6

p.G9_G10ins0

c.27_29dupTGG

Surrounding Variants

1 paper

NM_004333.6

p.G10G

c.30C>T

1 paper

NM_004333.6

p.G10G

c.30C>G

4 papers

NM_004333.6

p.G10insFs

c.28dupG

1 paper

NM_004333.6

p.G10_G11ins1

c.30_31insGGA

1 paper

NM_004333.6

p.G10G

c.30C>A

1 paper

NM_004333.6

p.G9del1

c.25_26delACC

2 papers

NM_004333.6

p.G10V

c.29G>T

3 papers

NM_004333.6

p.G10D

c.29G>A

2 papers

NM_004333.6

p.G11S

c.31G>A

2 papers

NM_004333.6

p.G10C

c.28G>T

2 papers

NM_004333.6

p.G9_G10insFs

c.27_28insT

1 paper

NM_004333.6

p.G11ins1

c.31_32insGAG