Varaico: Literature-Extracted Genetic Variants

BRAF

18,221 papers

RefSeq Summary

This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, ...

Pfam Domains

RBDaa 156–227UCSCRaf-like Ras-binding domain

C1_1aa 235–282UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PK_Tyr_Ser-Thraa 497–754UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

B-Raf proto-oncogene, serine/threonine kinase

HGNC Alias Symbols

BRAF1; BRAF-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_004333.6

p.G7D

c.20G>A

Surrounding Variants

2 papers

NM_004333.6

p.G7V

c.20G>T

1 paper

NM_004333.6

p.G7insFs

c.20_21ins19

1 paper

NM_004333.6

p.G7A

c.20G>C

1 paper

NM_004333.6

p.G7C

c.19G>T

4 papers

NM_004333.6

p.G7S

c.19G>A

1 paper

NM_004333.6

p.G7G

c.21C>T

1 paper

NM_004333.6

p.G7delFs

c.19delC

1 paper

NM_004333.6

p.G6insFs

c.16dupG

1 paper

NM_004333.6

p.G6G

c.18T>G

1 paper

NM_004333.6

p.G8S

c.22G>A

3 papers

NM_004333.6

p.G8V

c.23G>T

1 paper

NM_004333.6

p.G6V

c.17G>T