Varaico: Literature-Extracted Genetic Variants

BRAF

18,221 papers

RefSeq Summary

This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, ...

Pfam Domains

RBDaa 156–227UCSCRaf-like Ras-binding domain

C1_1aa 235–282UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PK_Tyr_Ser-Thraa 497–754UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

B-Raf proto-oncogene, serine/threonine kinase

HGNC Alias Symbols

BRAF1; BRAF-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004333.6

p.M1I

c.3G>A

Surrounding Variants

3 papers

NM_004333.6

p.M1I

c.3G>T

4 papers

NM_004333.6

p.M1insFs

c.2dupT

1 paper

NM_004333.6

p.M1fs

c.1_2fs

1 paper

NM_004333.6

p.M1_A2insFs

c.3_4insA

1 paper

NM_004333.6

p.M1I

c.3G>C

1 paper

NM_004333.6

p.M1insFs

c.2_3insG

2 papers

NM_004333.6

p.M1R

c.2T>G

3 papers

NM_004333.6

p.M1T

c.2T>C

1 paper

NM_004333.6

p.M1K

c.2T>A

1 paper

NM_004333.6

p.A2S

c.4G>T

1 paper

NM_004333.6

p.A2insFs

c.4_5insTT

1 paper

NM_004333.6

p.A2P

c.4G>C