Varaico: Literature-Extracted Genetic Variants

BRF1

107 papers

RefSeq Summary

This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encodin...

Pfam Domains

Zn_Ribbon_TFaa 4–46UCSCTFIIB zinc-binding

TFIIBaa 82–173UCSCTranscription factor TFIIB repeat

TFIIBaa 176–270UCSCTranscription factor TFIIB repeat

Gene Aliases

HGNC Name

BRF1 general transcription factor IIIB subunit

HGNC Previous Symbols

TAF3B2; TAF3C; GTF3B

Papers

RefSeq ID

Protein change

DNA change

1–12 of 133 variants

12 papers

NM_001519.4

p.S226L

c.677C>T

9 papers

NM_001519.4

p.R223W

c.667C>T

9 papers

NM_001519.4

p.P292H

c.875C>A

7 papers

NM_001519.4

p.T259M

c.776C>T

4 papers

NM_001519.4

p.V75M

c.223G>A

4 papers

NM_001519.4

p.C184fs

c.550_551fs

4 papers

NM_001519.4

p.C184delFs

c.551delC

4 papers

NM_001519.4

p.W218C

c.654G>C

4 papers

NM_001519.4

p.P292R

c.875C>G

4 papers

NM_001519.4

p.E487Splc

c.1459+2T>C

3 papers

NM_001519.4

p.R141C

c.421C>T

3 papers

NM_001519.4

p.W218G

c.652T>G