Varaico: Literature-Extracted Genetic Variants

BRF1

107 papers

RefSeq Summary

This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encodin...

Pfam Domains

Zn_Ribbon_TFaa 4–46UCSCTFIIB zinc-binding

TFIIBaa 82–173UCSCTranscription factor TFIIB repeat

TFIIBaa 176–270UCSCTranscription factor TFIIB repeat

Gene Aliases

HGNC Name

BRF1 general transcription factor IIIB subunit

HGNC Previous Symbols

TAF3B2; TAF3C; GTF3B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_001519.4

p.E487Splc

c.1459+2T>C

Surrounding Variants

1 paper

NM_001519.4

p.R486R

c.1456A>C

1 paper

NM_001519.4

p.E484A

c.1451A>C

1 paper

NM_001519.4

p.E472K

c.1414G>A

1 paper

NM_001519.4

p.K470R

c.1409A>G

1 paper

NM_001519.4

p.A467T

c.1399G>A

1 paper

NM_001519.4

p.Y460fs

c.1378_1379fs

1 paper

NM_001519.4

p.Y501C

c.1502A>G

1 paper

NM_001519.4

p.L449_G451del3

c.1345_1352del9

2 papers

NM_001519.4

p.P506T

c.1516C>A

2 papers

NM_001519.4

p.E526K

c.1576G>A

1 paper

NM_001519.4

p.M528I

c.1584G>A

1 paper

NM_001519.4

p.S535Y

c.1604C>A