Varaico: Literature-Extracted Genetic Variants

BRF1

107 papers

RefSeq Summary

This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encodin...

Pfam Domains

Zn_Ribbon_TFaa 4–46UCSCTFIIB zinc-binding

TFIIBaa 82–173UCSCTranscription factor TFIIB repeat

TFIIBaa 176–270UCSCTranscription factor TFIIB repeat

Gene Aliases

HGNC Name

BRF1 general transcription factor IIIB subunit

HGNC Previous Symbols

TAF3B2; TAF3C; GTF3B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001519.4

p.H130H

c.390C>T

Surrounding Variants

1 paper

NM_001519.4

p.V131M

c.391G>A

1 paper

NM_001519.4

p.L138P

c.413T>C

1 paper

NM_001519.4

p.V139L

c.415G>C

1 paper

NM_001519.4

p.C140S

c.418T>A

1 paper

NM_001519.4

p.C140S

c.419G>C

3 papers

NM_001519.4

p.R141C

c.421C>T

1 paper

NM_001519.4

p.R141H

c.422G>A

1 paper

NM_001519.4

p.T142A

c.424A>G

2 papers

NM_001519.4

p.T109I

c.326C>T

1 paper

NM_001519.4

p.H105H

c.315C>T

1 paper

NM_001519.4

p.Q101*

c.301C>T

1 paper

NM_001519.4

p.R91H

c.272G>A