Varaico: Literature-Extracted Genetic Variants

BRF1

107 papers

RefSeq Summary

This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encodin...

Pfam Domains

Zn_Ribbon_TFaa 4–46UCSCTFIIB zinc-binding

TFIIBaa 82–173UCSCTranscription factor TFIIB repeat

TFIIBaa 176–270UCSCTranscription factor TFIIB repeat

Gene Aliases

HGNC Name

BRF1 general transcription factor IIIB subunit

HGNC Previous Symbols

TAF3B2; TAF3C; GTF3B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001519.4

p.Q84*

c.250C>T

Surrounding Variants

1 paper

NM_001519.4

p.S81T

c.241T>A

1 paper

NM_001519.4

p.Q87H

c.261G>C

1 paper

NM_001519.4

p.E80Q

c.238G>C

4 papers

NM_001519.4

p.V75M

c.223G>A

1 paper

NM_001519.4

p.G70C

c.208G>T

1 paper

NM_001519.4

p.P67R

c.200C>G

1 paper

NM_001519.4

p.A63Fs

c.187delinsGTGATGGTGGAFs