carbonic anhydrase 12

HsT18816

carbonic anhydrase XII

Carbonic anhydrase 12

Carbonate dehydratase XII

Carbonic anhydrase XII

Tumor antigen HOM-RCC-3.1.3

CA-XII

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2014].

Varaico: Literature-Extracted Genetic Variants

CA12

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbol