Varaico: Literature-Extracted Genetic Variants

Gene:CASP1
Variant:p.D92Y

CASP1

574 papers

RefSeq Summary

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. ...

Pfam Domains

CARDaa 3–90UCSCCaspase recruitment domain
CARDaa 3–90UCSCCaspase recruitment domain
Peptidase_C14aa 162–399UCSCCaspase domain

Gene Aliases

HGNC Name

caspase 1

HGNC Previous Symbol

IL1BC

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001257118.3
p.D92Y
c.274G>T
Surrounding Variants
1 paper
NM_001257118.3
p.S90A
c.268T>G
1 paper
NM_001257118.3
p.L89I
c.265C>A
1 paper
NM_001257118.3
p.T86T
c.258G>A
1 paper
NM_001257118.3
p.G85W
c.253G>T
2 papers
NM_001257118.3
p.G85R
c.253G>C
2 papers
NM_001257118.3
p.G85R
c.253G>A
2 papers
NM_001257118.3
p.D80N
c.238G>A
1 paper
NM_001257118.3
p.Y75H
c.223T>C
1 paper
NM_001257118.3
p.Y75N
c.223T>A
1 paper
NM_001257118.3
p.A68P
c.202G>C
2 papers
NM_001257118.3
p.A66V
c.197C>T
1 paper
NM_001257118.3
p.K64E
c.190A>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."