Varaico: Literature-Extracted Genetic Variants

Gene:CASP1
Variant:p.N36Y

CASP1

574 papers

RefSeq Summary

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. ...

Pfam Domains

CARDaa 3–90UCSCCaspase recruitment domain
CARDaa 3–90UCSCCaspase recruitment domain
Peptidase_C14aa 162–399UCSCCaspase domain

Gene Aliases

HGNC Name

caspase 1

HGNC Previous Symbol

IL1BC

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001257118.3
p.N36Y
c.106A>T
Surrounding Variants
1 paper
NM_001257118.3
p.L35P
c.104T>C
1 paper
NM_001257118.3
p.K37*
c.109A>T
1 paper
NM_001257118.3
p.K37E
c.109A>G
3 papers
NM_001257118.3
p.K37Q
c.109A>C
1 paper
NM_001257118.3
p.K37N
c.111G>T
1 paper
NM_001257118.3
p.K37N
c.111G>C
1 paper
NM_001257118.3
p.I22_R33del12
c.64_98del36
1 paper
NM_001257118.3
p.Q31H
c.93G>C
6 papers
NM_001257118.3
p.Q31Q
c.93G>A
1 paper
NM_001257118.3
p.L30F
c.90A>T
3 papers
NM_001257118.3
p.E41A
c.122A>C
1 paper
NM_001257118.3
p.L30F
c.90A>C
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