Varaico: Literature-Extracted Genetic Variants

Gene:CASP10
Variant:p.G45*

CASP10

247 papers

RefSeq Summary

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. ...

Pfam Domains

DEDaa 20–101UCSCDeath effector domain
DEDaa 115–191UCSCDeath effector domain
Peptidase_C14aa 283–505UCSCCaspase domain

Gene Aliases

HGNC Name

caspase 10

HGNC Alias Symbols

MCH4; FLICE-2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_032977.4
p.G45*
c.133G>T
Surrounding Variants
1 paper
NM_032977.4
p.C43S
c.128G>C
1 paper
NM_032977.4
p.L52L
c.154C>T
1 paper
NM_032977.4
p.E37D
c.111G>C
1 paper
NM_032977.4
p.E53G
c.158A>G
1 paper
NM_032977.4
p.D35delFs
c.104delA
1 paper
NM_032977.4
p.D35fs
c.103_104fs
2 papers
NM_032977.4
p.S57S
c.171A>G
1 paper
NM_032977.4
p.G32R
c.94G>A
1 paper
NM_032977.4
p.S59L
c.176C>T
1 paper
NM_032977.4
p.S59S
c.177A>G
1 paper
NM_032977.4
p.N30Y
c.88A>T
1 paper
NM_032977.4
p.E63*
c.187G>T
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