Varaico: Literature-Extracted Genetic Variants

Gene:CASP10
Variant:p.S59S

CASP10

247 papers

RefSeq Summary

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. ...

Pfam Domains

DEDaa 20–101UCSCDeath effector domain
DEDaa 115–191UCSCDeath effector domain
Peptidase_C14aa 283–505UCSCCaspase domain

Gene Aliases

HGNC Name

caspase 10

HGNC Alias Symbols

MCH4; FLICE-2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_032977.4
p.S59S
c.177A>G
Surrounding Variants
1 paper
NM_032977.4
p.S59L
c.176C>T
2 papers
NM_032977.4
p.S57S
c.171A>G
1 paper
NM_032977.4
p.E63*
c.187G>T
1 paper
NM_032977.4
p.E53G
c.158A>G
1 paper
NM_032977.4
p.L52L
c.154C>T
1 paper
NM_032977.4
p.E68D
c.204G>C
1 paper
NM_032977.4
p.E68D
c.204G>T
1 paper
NM_032977.4
p.L70V
c.208C>G
1 paper
NM_032977.4
p.E73*
c.217G>T
1 paper
NM_032977.4
p.E74G
c.221A>G
1 paper
NM_032977.4
p.G45*
c.133G>T
1 paper
NM_032977.4
p.C43S
c.128G>C
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