Varaico: Literature-Extracted Genetic Variants

Gene:CASP10
Variant:p.P228_Q229Splc

CASP10

247 papers

RefSeq Summary

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. ...

Pfam Domains

DEDaa 20–101UCSCDeath effector domain
DEDaa 115–191UCSCDeath effector domain
Peptidase_C14aa 283–505UCSCCaspase domain

Gene Aliases

HGNC Name

caspase 10

HGNC Alias Symbols

MCH4; FLICE-2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_032977.4
p.P228_Q229Splc
c.684+4G>A
Surrounding Variants
1 paper
NM_032977.4
p.P228_Q229Splc
c.684+1G>A
4 papers
NM_032977.4
p.P228L
c.683C>T
1 paper
NM_032977.4
p.L224L
c.672G>A
1 paper
NM_032977.4
p.L224*
c.671T>A
1 paper
NM_032977.4
p.V220fs
c.658_659fs
1 paper
NM_032977.4
p.T218I
c.653C>T
1 paper
NM_032977.4
p.E211K
c.631G>A
1 paper
NM_032977.4
p.E211fs
c.631_632fs
1 paper
NM_032977.4
p.E211*
c.631G>T
1 paper
NM_032977.4
p.P199R
c.596C>G
1 paper
NM_032977.4
p.A193Splc
c.578-3C>T
1 paper
NM_032977.4
p.P228_Q229Splc
c.684+149C>T
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