Varaico: Literature-Extracted Genetic Variants

Gene:CASP10
Variant:p.K271_R272Splc

CASP10

247 papers

RefSeq Summary

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. ...

Pfam Domains

DEDaa 20–101UCSCDeath effector domain
DEDaa 115–191UCSCDeath effector domain
Peptidase_C14aa 283–505UCSCCaspase domain

Gene Aliases

HGNC Name

caspase 10

HGNC Alias Symbols

MCH4; FLICE-2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_032977.4
p.K271_R272Splc
c.813+2T>C
Surrounding Variants
1 paper
NM_032977.4
p.N265S
c.794A>G
1 paper
NM_032977.4
p.N262Y
c.784A>T
1 paper
NM_032977.4
p.Q257*
c.769C>T
1 paper
NM_032977.4
p.G255G
c.765G>C
1 paper
NM_032977.4
p.G255_E267delFs
c.765_799del35
1 paper
NM_032977.4
p.S253F
c.758C>T
1 paper
NM_032977.4
p.L251L
c.753G>T
1 paper
NM_032977.4
p.S250S
c.750C>T
1 paper
NM_032977.4
p.S250N
c.749G>A
1 paper
NM_032977.4
p.A248S
c.742G>T
1 paper
NM_032977.4
p.K271_R272Splc
c.814-88C>T
1 paper
NM_032977.4
p.K271_R272Splc
c.814-2A>G
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