Varaico: Literature-Extracted Genetic Variants

Gene:CASP10
Variant:p.L285F

CASP10

247 papers

RefSeq Summary

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. ...

Pfam Domains

DEDaa 20–101UCSCDeath effector domain
DEDaa 115–191UCSCDeath effector domain
Peptidase_C14aa 283–505UCSCCaspase domain

Gene Aliases

HGNC Name

caspase 10

HGNC Alias Symbols

MCH4; FLICE-2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
10 papers
NM_032977.4
p.L285F
c.853C>T
Surrounding Variants
1 paper
NM_032977.4
p.L285I
c.853C>A
1 paper
NM_032977.4
p.L285P
c.854T>C
1 paper
NM_032977.4
p.H282Y
c.844C>T
2 papers
NM_032977.4
p.N279N
c.837T>C
2 papers
NM_032977.4
p.S296F
c.887C>T
1 paper
NM_032977.4
p.K271_R272Splc
c.814-2A>G
1 paper
NM_032977.4
p.K305E
c.913A>G
1 paper
NM_032977.4
p.A307fs
c.919_920fs
1 paper
NM_032977.4
p.K271_R272Splc
c.814-88C>T
1 paper
NM_032977.4
p.E308Splc
c.923-3C>T
1 paper
NM_032977.4
p.E308E
c.924G>A
1 paper
NM_032977.4
p.L310L
c.928C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."