Varaico: Literature-Extracted Genetic Variants

Gene:CASP10
Variant:p.M334_L336del3

CASP10

247 papers

RefSeq Summary

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. ...

Pfam Domains

DEDaa 20–101UCSCDeath effector domain
DEDaa 115–191UCSCDeath effector domain
Peptidase_C14aa 283–505UCSCCaspase domain

Gene Aliases

HGNC Name

caspase 10

HGNC Alias Symbols

MCH4; FLICE-2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_032977.4
p.M334_L336del3
c.1000_1007del9
Surrounding Variants
1 paper
NM_032977.4
p.M334_L336delFs
c.1001_1007del7
1 paper
NM_032977.4
p.V335I
c.1003G>A
1 paper
NM_032977.4
p.V335Fs
c.1003delinsGAFs
1 paper
NM_032977.4
p.L336delFs
c.1008delG
1 paper
NM_032977.4
p.L336L
c.1008G>T
1 paper
NM_032977.4
p.Q337insFs
c.1010_1011insA
1 paper
NM_032977.4
p.T328M
c.983C>T
1 paper
NM_032977.4
p.K340E
c.1018A>G
1 paper
NM_032977.4
p.P343delFs
c.1027delC
1 paper
NM_032977.4
p.G318E
c.953G>A
1 paper
NM_032977.4
p.W316fs
c.946_947fs
1 paper
NM_032977.4
p.V352insFs
c.1054dupG
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."