Varaico: Literature-Extracted Genetic Variants

Gene:CASP3
Variant:p.F256del1

CASP3

926 papers

RefSeq Summary

The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) p...

Pfam Domains

Peptidase_C14aa 44–274UCSCCaspase domain

Gene Aliases

HGNC Name

caspase 3

HGNC Alias Symbols

CPP32; CPP32B; Yama; apopain

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004346.4
p.F256del1
c.766_768delAAA
Surrounding Variants
1 paper
NM_004346.4
p.D253D
c.759C>T
1 paper
NM_004346.4
p.Q261*
c.781C>T
1 paper
NM_004346.4
p.I262N
c.785T>A
1 paper
NM_004346.4
p.P263Q
c.788C>A
1 paper
NM_004346.4
p.S249C
c.746C>G
3 papers
NM_004346.4
p.S249A
c.745T>G
1 paper
NM_004346.4
p.V266I
c.796G>A
1 paper
NM_004346.4
p.E248K
c.742G>A
1 paper
NM_004346.4
p.V266A
c.797T>C
1 paper
NM_004346.4
p.V266delFs
c.797delA
1 paper
NM_004346.4
p.T255_S267delFs
c.765_799del35
1 paper
NM_004346.4
p.E246A
c.737A>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."