Varaico: Literature-Extracted Genetic Variants

Gene:CASP3
Variant:p.G132E

CASP3

926 papers

RefSeq Summary

The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) p...

Pfam Domains

Peptidase_C14aa 44–274UCSCCaspase domain

Gene Aliases

HGNC Name

caspase 3

HGNC Alias Symbols

CPP32; CPP32B; Yama; apopain

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004346.4
p.G132E
c.395G>A
Surrounding Variants
1 paper
NM_004346.4
p.P133S
c.397C>T
1 paper
NM_004346.4
p.V134A
c.401T>C
1 paper
NM_004346.4
p.V134V
c.402T>A
1 paper
NM_004346.4
p.G129E
c.386G>A
1 paper
NM_004346.4
p.D135G
c.404A>G
1 paper
NM_004346.4
p.L136P
c.407T>C
1 paper
NM_004346.4
p.D135_L136del2
c.403_407del6
1 paper
NM_004346.4
p.I127N
c.380T>A
1 paper
NM_004346.4
p.I139T
c.416T>C
2 papers
NM_004346.4
p.E124A
c.371A>C
3 papers
NM_004346.4
p.N141I
c.422A>T
1 paper
NM_004346.4
p.N141S
c.422A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."