Varaico: Literature-Extracted Genetic Variants

Gene:CASP3
Variant:p.K11I

CASP3

926 papers

RefSeq Summary

The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) p...

Pfam Domains

Peptidase_C14aa 44–274UCSCCaspase domain

Gene Aliases

HGNC Name

caspase 3

HGNC Alias Symbols

CPP32; CPP32B; Yama; apopain

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004346.4
p.K11I
c.32A>T
Surrounding Variants
1 paper
NM_004346.4
p.K11R
c.32A>G
2 papers
NM_004346.4
p.S12T
c.34T>A
1 paper
NM_004346.4
p.S10insFs
c.29_30insA
1 paper
NM_004346.4
p.S10T
c.28T>A
2 papers
NM_004346.4
p.D9delFs
c.26delT
4 papers
NM_004346.4
p.D9A
c.26A>C
1 paper
NM_004346.4
p.K14_N15insT
c.40_44ins3
1 paper
NM_004346.4
p.K14_N15insFs
c.42_43insG
1 paper
NM_004346.4
p.S7S
c.21A>G
1 paper
NM_004346.4
p.N15S
c.44A>G
1 paper
NM_004346.4
p.S10_N15delFs
c.28_44del17
1 paper
NM_004346.4
p.N6K
c.18C>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."