Varaico: Literature-Extracted Genetic Variants

Gene:CASP3
Variant:p.E5del1

CASP3

926 papers

RefSeq Summary

The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) p...

Pfam Domains

Peptidase_C14aa 44–274UCSCCaspase domain

Gene Aliases

HGNC Name

caspase 3

HGNC Alias Symbols

CPP32; CPP32B; Yama; apopain

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004346.4
p.E5del1
c.13_14delTTC
Surrounding Variants
1 paper
NM_004346.4
p.N6K
c.18C>G
1 paper
NM_004346.4
p.E5insFs
c.14_15insT
1 paper
NM_004346.4
p.E5*
c.13G>T
1 paper
NM_004346.4
p.E5Q
c.13G>C
1 paper
NM_004346.4
p.S7S
c.21A>G
1 paper
NM_004346.4
p.T4S
c.10A>T
1 paper
NM_004346.4
p.T4A
c.10A>G
2 papers
NM_004346.4
p.E2D
c.6G>T
1 paper
NM_004346.4
p.E2D
c.6G>C
4 papers
NM_004346.4
p.D9A
c.26A>C
2 papers
NM_004346.4
p.D9delFs
c.26delT
1 paper
NM_004346.4
p.S10T
c.28T>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."