Varaico: Literature-Extracted Genetic Variants

Gene:CASP4
Variant:p.Y372fs

CASP4

91 papers

RefSeq Summary

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. C...

Pfam Domains

CARDaa 3–86UCSCCaspase recruitment domain
CARDaa 3–86UCSCCaspase recruitment domain
Peptidase_C14aa 135–372UCSCCaspase domain

Gene Aliases

HGNC Name

caspase 4

HGNC Alias Symbols

ICE(rel)II; ICH-2; TX

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001225.4
p.Y372fs
c.1114_1115fs
Surrounding Variants
3 papers
NM_001225.4
p.F371Fs
c.1113delinsTCFs
1 paper
NM_001225.4
p.F371fs
c.1111_1112fs
1 paper
NM_001225.4
p.S366A
c.1096T>G
2 papers
NM_001225.4
p.L365V
c.1093C>G
1 paper
NM_001225.4
p.K356delFs
c.1068delT
1 paper
NM_001225.4
p.K356fs
c.1066_1067fs
1 paper
NM_001225.4
p.P353L
c.1058C>T
1 paper
NM_001225.4
p.E351Q
c.1051G>C
1 paper
NM_001225.4
p.Q347*
c.1039C>T
1 paper
NM_001225.4
p.K345_V346Splc
c.1036-374T>C
1 paper
NM_001225.4
p.R344W
c.1030C>T
1 paper
NM_001225.4
p.H338R
c.1013A>G
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