Varaico: Literature-Extracted Genetic Variants

Gene:CCDC50
Variant:p.K226K

CCDC50

85 papers

RefSeq Summary

This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural...

Pfam Domains

CCDC50_Naa 4–128UCSCCoiled-coil domain-containing protein 50 N-terminus

Gene Aliases

HGNC Name

coiled-coil domain containing 50

HGNC Previous Symbol

DFNA44

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_178335.3
p.K226K
c.678A>G
Surrounding Variants
1 paper
NM_178335.3
p.E224D
c.672A>C
1 paper
NM_178335.3
p.E224D
c.672A>T
1 paper
NM_178335.3
p.R232G
c.694A>G
3 papers
NM_178335.3
p.H217H
c.651T>C
1 paper
NM_178335.3
p.L237V
c.709C>G
1 paper
NM_178335.3
p.L237L
c.711G>C
1 paper
NM_178335.3
p.S207C
c.620C>G
1 paper
NM_178335.3
p.S199L
c.596C>T
1 paper
NM_178335.3
p.W254R
c.760T>C
1 paper
NM_178335.3
p.E255G
c.764A>G
1 paper
NM_178335.3
p.Q196P
c.587A>C
1 paper
NM_178335.3
p.I258V
c.772A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."