Varaico: Literature-Extracted Genetic Variants

CCN1

93 papers

RefSeq Summary

The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate prote...

Pfam Domains

IGFBPaa 26–78UCSCInsulin-like growth factor binding protein

VWCaa 100–163UCSCvon Willebrand factor type C domain

TSP1_CCNaa 229–272UCSCCCN3 Nov like TSP1 domain

Cys_knotaa 283–375UCSCCystine-knot domain

Gene Aliases

HGNC Name

cellular communication network factor 1

HGNC Previous Symbols

IGFBP10; CYR61

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_001554.5

p.R334W

c.1000C>T

Surrounding Variants

1 paper

NM_001554.5

p.C337Y

c.1010G>A

1 paper

NM_001554.5

p.D339N

c.1015G>A

1 paper

NM_001554.5

p.M348T

c.1043T>C

8 papers

NM_001554.5

p.S316C

c.947C>G

1 paper

NM_001554.5

p.G315R

c.943G>C

1 paper

NM_001554.5

p.P360P

c.1080G>A

1 paper

NM_001554.5

p.Y300Y

c.900C>T

1 paper

NM_001554.5

p.R371T

c.1112G>C

1 paper

NM_001554.5

p.K378K

c.1134A>G

1 paper

NM_001554.5

p.K288insFs

c.863_864insAC

1 paper

NM_001554.5

p.K284N

c.852G>C

1 paper

NM_001554.5

p.K284N

c.852G>T