Varaico: Literature-Extracted Genetic Variants

CCN2

187 papers

RefSeq Summary

The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many c...

Pfam Domains

IGFBPaa 29–82UCSCInsulin-like growth factor binding protein

VWCaa 103–166UCSCvon Willebrand factor type C domain

TSP1_CCNaa 199–242UCSCCCN3 Nov like TSP1 domain

Cys_knotaa 253–346UCSCCystine-knot domain

Gene Aliases

HGNC Name

cellular communication network factor 2

HGNC Previous Symbol

CTGF

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001901.4

p.K255N

c.765G>C

Surrounding Variants

2 papers

NM_001901.4

p.K255N

c.765G>T

1 paper

NM_001901.4

p.G253D

c.758G>A

1 paper

NM_001901.4

p.P260_I262delFs

c.779_786del8

1 paper

NM_001901.4

p.C273C

c.819C>T

1 paper

NM_001901.4

p.Y279H

c.835T>C

1 paper

NM_001901.4

p.T288insFs

c.863_864insAC

1 paper

NM_001901.4

p.C292S

c.874T>A

1 paper

NM_001901.4

p.H296fs

c.886_887fs

1 paper

NM_001901.4

p.T300T

c.900C>G

1 paper

NM_001901.4

p.P302S

c.904C>T

1 paper

NM_001901.4

p.P302T

c.904C>A

2 papers

NM_001901.4

p.V303L

c.907G>T