Varaico: Literature-Extracted Genetic Variants

CCN2

187 papers

RefSeq Summary

The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many c...

Pfam Domains

IGFBPaa 29–82UCSCInsulin-like growth factor binding protein

VWCaa 103–166UCSCvon Willebrand factor type C domain

TSP1_CCNaa 199–242UCSCCCN3 Nov like TSP1 domain

Cys_knotaa 253–346UCSCCystine-knot domain

Gene Aliases

HGNC Name

cellular communication network factor 2

HGNC Previous Symbol

CTGF

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001901.4

p.K232E

c.694A>G

Surrounding Variants

1 paper

NM_001901.4

p.K232R

c.695A>G

1 paper

NM_001901.4

p.K251_K252Splc

c.753+3A>G

1 paper

NM_001901.4

p.A208_C209insFs

c.624_625insA

1 paper

NM_001901.4

p.A208_C209insA

c.622_626ins3

1 paper

NM_001901.4

p.V201I

c.601G>A

1 paper

NM_001901.4

p.A181delFs

c.543delA

1 paper

NM_001901.4

p.Y182H

c.544T>C

1 paper

NM_001901.4

p.K170R

c.509A>G

1 paper

NM_001901.4

p.G158_K159ins6

c.472_476ins18

1 paper

NM_001901.4

p.R153S

c.459G>T

1 paper

NM_001901.4

p.R153S

c.459G>C

1 paper

NM_001901.4

p.R152W

c.454A>T