Varaico: Literature-Extracted Genetic Variants

CCN2

187 papers

RefSeq Summary

The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many c...

Pfam Domains

IGFBPaa 29–82UCSCInsulin-like growth factor binding protein

VWCaa 103–166UCSCvon Willebrand factor type C domain

TSP1_CCNaa 199–242UCSCCCN3 Nov like TSP1 domain

Cys_knotaa 253–346UCSCCystine-knot domain

Gene Aliases

HGNC Name

cellular communication network factor 2

HGNC Previous Symbol

CTGF

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001901.4

p.S112S

c.336C>T

Surrounding Variants

1 paper

NM_001901.4

p.S115S

c.345C>T

1 paper

NM_001901.4

p.K121Q

c.361A>C

1 paper

NM_001901.4

p.K121N

c.363G>C

1 paper

NM_001901.4

p.Y122H

c.364T>C

1 paper

NM_001901.4

p.C103Y

c.308G>A

1 paper

NM_001901.4

p.A97S

c.289G>T

1 paper

NM_001901.4

p.A130A

c.390G>T

1 paper

NM_001901.4

p.G132D

c.395G>A

1 paper

NM_001901.4

p.D140Y

c.418G>T

1 paper

NM_001901.4

p.C148Y

c.443G>A

1 paper

NM_001901.4

p.R152W

c.454A>T

1 paper

NM_001901.4

p.R153S

c.459G>T