Varaico: Literature-Extracted Genetic Variants

Gene:CCNB1
Variant:p.E84K

CCNB1

211 papers

RefSeq Summary

The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). The encoded protein is necessary ...

Pfam Domains

Cyclin_Naa 173–298UCSCCyclin, N-terminal domain
Cyclin_Caa 300–418UCSCCyclin, C-terminal domain

Gene Aliases

HGNC Name

cyclin B1

HGNC Alias Name

G2/mitotic-specific cyclin B1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_031966.4
p.E84K
c.250G>A
Surrounding Variants
1 paper
NM_031966.4
p.E84G
c.251A>G
1 paper
NM_031966.4
p.L83L
c.249T>C
1 paper
NM_031966.4
p.E84E
c.252A>G
1 paper
NM_031966.4
p.K85E
c.253A>G
1 paper
NM_031966.4
p.L83F
c.247C>T
1 paper
NM_031966.4
p.K85R
c.254A>G
1 paper
NM_031966.4
p.K85K
c.255G>A
1 paper
NM_031966.4
p.V86I
c.256G>A
1 paper
NM_031966.4
p.V86A
c.257T>C
1 paper
NM_031966.4
p.K81R
c.242A>G
1 paper
NM_031966.4
p.V86V
c.258A>G
1 paper
NM_031966.4
p.K81E
c.241A>G
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