Varaico: Literature-Extracted Genetic Variants

Gene:CCNB1
Variant:p.P117S

CCNB1

211 papers

RefSeq Summary

The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). The encoded protein is necessary ...

Pfam Domains

Cyclin_Naa 173–298UCSCCyclin, N-terminal domain
Cyclin_Caa 300–418UCSCCyclin, C-terminal domain

Gene Aliases

HGNC Name

cyclin B1

HGNC Alias Name

G2/mitotic-specific cyclin B1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_031966.4
p.P117S
c.349C>T
Surrounding Variants
1 paper
NM_031966.4
p.P117L
c.350C>T
1 paper
NM_031966.4
p.S116L
c.347C>T
1 paper
NM_031966.4
p.L115P
c.344T>C
1 paper
NM_031966.4
p.L115F
c.343C>T
1 paper
NM_031966.4
p.P119P
c.357T>C
1 paper
NM_031966.4
p.K114E
c.340A>G
1 paper
NM_031966.4
p.E113E
c.339A>G
1 paper
NM_031966.4
p.I120T
c.359T>C
1 paper
NM_031966.4
p.E113G
c.338A>G
1 paper
NM_031966.4
p.I120I
c.360T>C
1 paper
NM_031966.4
p.I120M
c.360T>G
1 paper
NM_031966.4
p.E113K
c.337G>A
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