Varaico: Literature-Extracted Genetic Variants

Gene:CCNB1
Variant:p.I120T

CCNB1

211 papers

RefSeq Summary

The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). The encoded protein is necessary ...

Pfam Domains

Cyclin_Naa 173–298UCSCCyclin, N-terminal domain
Cyclin_Caa 300–418UCSCCyclin, C-terminal domain

Gene Aliases

HGNC Name

cyclin B1

HGNC Alias Name

G2/mitotic-specific cyclin B1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_031966.4
p.I120T
c.359T>C
Surrounding Variants
1 paper
NM_031966.4
p.I120I
c.360T>C
1 paper
NM_031966.4
p.I120M
c.360T>G
1 paper
NM_031966.4
p.P119P
c.357T>C
1 paper
NM_031966.4
p.L121L
c.361T>C
1 paper
NM_031966.4
p.L121S
c.362T>C
1 paper
NM_031966.4
p.L121L
c.363G>A
1 paper
NM_031966.4
p.L121F
c.363G>C
1 paper
NM_031966.4
p.L121_V122Splc
c.363+1G>A
1 paper
NM_031966.4
p.L121_V122Splc
c.363+2T>C
1 paper
NM_031966.4
p.P117L
c.350C>T
1 paper
NM_031966.4
p.P117S
c.349C>T
1 paper
NM_031966.4
p.S116L
c.347C>T
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