Varaico: Literature-Extracted Genetic Variants

Gene:CCNB1
Variant:p.F146S

CCNB1

211 papers

RefSeq Summary

The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). The encoded protein is necessary ...

Pfam Domains

Cyclin_Naa 173–298UCSCCyclin, N-terminal domain
Cyclin_Caa 300–418UCSCCyclin, C-terminal domain

Gene Aliases

HGNC Name

cyclin B1

HGNC Alias Name

G2/mitotic-specific cyclin B1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_031966.4
p.F146S
c.437T>C
Surrounding Variants
1 paper
NM_031966.4
p.F146F
c.438C>T
1 paper
NM_031966.4
p.S147P
c.439T>C
1 paper
NM_031966.4
p.S147F
c.440C>T
1 paper
NM_031966.4
p.S147S
c.441T>C
1 paper
NM_031966.4
p.D148N
c.442G>A
1 paper
NM_031966.4
p.Q144R
c.431A>G
1 paper
NM_031966.4
p.D148G
c.443A>G
1 paper
NM_031966.4
p.Q144*
c.430C>T
1 paper
NM_031966.4
p.D148D
c.444T>C
1 paper
NM_031966.4
p.V149I
c.445G>A
1 paper
NM_031966.4
p.C143C
c.429T>C
1 paper
NM_031966.4
p.C143Y
c.428G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."